VitroFlow

Tag Name: VitroFlow

Discover VitroFlow — a programmable closed-loop microfluidic perfusion pump engineered to generate stable continuous flow for advanced tissue engineering, drug development, and organ-on-chip research.

Introduction

VitroFlow is a compact and programmable perfusion platform designed to address the limitations of conventional perfusion pumps such as syringe and peristaltic pumps used in microfluidics and biomedical research.

Traditional syringe pumps operate in an open-loop configuration and are limited in generating long-duration continuous flows while peristaltic pumps can only generate continuous flows with minimal control on the flow profile. VitroFlow transforms this process by integrating a closed-loop circulation mechanism into a syringe pump that allows continuous and precisely controlled perfusion between a syringe and a fluid reservoir.

By enabling customizable flow profiles, stable long-term perfusion, and real-time monitoring, VitroFlow provides a powerful tool for researchers working in microfluidics, tissue engineering, mechanobiology, and pharmaceutical testing.

This innovation enables more reliable experimental conditions and supports the development of next-generation biomedical research platforms including organ-on-chip systems.

Inventors

1 Assoc. Prof. Dr. Huseyin C. Yalcin

Main Features

Closed-Loop Continuous Perfusion

Transforms a traditional syringe pump into a continuous flow generator using an integrated dual-valve circulation mechanism.

Programmable Flow Control

Allows precise control of flow rate, frequency, and waveform through a computer interface.

Real-Time Monitoring

Built-in display enables continuous observation of flow parameters and system status.

Portable and Flexible Operation

Operates through either battery power or electrical supply for both lab and portable applications.

Microfluidics Compatibility

Designed to integrate seamlessly with microfluidic chips and cell culture platforms.

Strategic Opportunities

Regenerative Medicine & Tissue Engineering

Supports perfusion systems required for tissue growth and organ-on-chip technologies.

Pharmaceutical Development & Drug Testing

Enables controlled microfluidic environments for drug screening and pharmacological studies.

Mechanobiology Research

Provides controlled fluid forces for studying cellular responses to mechanical stimuli.

Personalized Medicine

Facilitates patient-specific drug response testing using microfluidic platforms.

Value Proposition

Stable Continuous Flow Generation

Enables reliable long-term perfusion required for advanced biological experiments.

Compact & User-Friendly Design

Easy to operate with a programmable interface and integrated monitoring.

Cost-Effective Research Platform

Enhances the capability of existing syringe pumps without expensive equipment.

Research Scalability

Adaptable for integration across multiple biomedical research platforms.

Status of the Invention

Intellectual Property Filed: QU2025-005

U.S. Provisional Patent Application No. 63/870,023

Technology validated in laboratory environment

Technology Readiness Level: TRL 5–6

Invitation to Industry — Collaborate With Us

Join us in advancing next-generation biomedical research systems. VitroFlow is ready for:

Licensing & commercialization

Integration with microfluidic research platforms

Pharmaceutical and biomedical research collaborations

Organ-on-chip technology partnerships

Research equipment manufacturing partnerships

With strong research backing from Qatar University, VitroFlow represents a powerful and scalable solution for precision microfluidic perfusion and advanced biomedical experimentation.

More Information

Connect With Us

Innovation Office — Qatar University | +974-4403-7197 | QU.IP@qu.edu.qa

IP Number: QU2025-005

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